The effect of apricots on the experimental cataract model formed by sodium selenite


Doganay S., Duz C., FIRAT P. G. , Cankaya C. , Kutukde D., ÇİĞREMİŞ Y.

FOOD AND CHEMICAL TOXICOLOGY, cilt.55, ss.371-377, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 55
  • Basım Tarihi: 2013
  • Doi Numarası: 10.1016/j.fct.2012.12.061
  • Dergi Adı: FOOD AND CHEMICAL TOXICOLOGY
  • Sayfa Sayıları: ss.371-377

Özet

This study was designed in order to investigate whether sun dried apricots have a preventive effect on the experimental cataract model formed by sodium selenite in rats. Fifty-nine Spraque-Dawley rat pups were divided into three groups. Group I (control group) consisted of twenty rat pups, born from the rats nourished ad libitum. Group 2 consisted of 18 newborn rats, born from the rats nourished ad libitum with 10% sun dried natural apricots. Group 3 consisted of 21 newborn rats, born from the rats nourished ad libitum. Subcutaneous (30 nmol/gr) sodium selenite injection was applied to all the newborn rats except the control group (Group 1) on postpartum day 10. Cataract development was graded by slit-lamp examination and photography. Encapsulated lenses were analyzed for reduced glutathione (GSH) and malondialdehyde (MDA), a marker of lipid per oxidation.