Antioxidative effect of melationin, ascorbic acid and N-acetylcysteine on caerulein-induced pancreatitis and associated liver injury in rats

Esrefoglu M., Gul M., Ates B., Batcioglu K., Selimoglu M. A.

WORLD JOURNAL OF GASTROENTEROLOGY, vol.12, no.2, pp.259-264, 2006 (SCI-Expanded) identifier

  • Publication Type: Article / Article
  • Volume: 12 Issue: 2
  • Publication Date: 2006
  • Journal Name: WORLD JOURNAL OF GASTROENTEROLOGY
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.259-264
  • Keywords: caerulein, liver, melatonin, oxidative stress, pancreatitis, FREE-RADICAL SCAVENGERS, OXYGEN-FREE RADICALS, ASCITIC FLUID, OXIDATIVE STRESS, MELATONIN, PATHOGENESIS, DYSFUNCTION, TRYPTOPHAN, MODEL
  • Inonu University Affiliated: Yes

Abstract

AIM: To investigate the role of oxidative injury in pancreatitis-induced hepatic damage and the effect of antioxidant agents such as melatonin, ascorbic acid and N-acetyl cysteine on caerulein-incluced pancreatitis and associated liver injury in rats.