IL-4, TGF-beta, NF-kappa B and MPO levels in Patients with Treatment Resistant Schizophrenia

KARTALCI Ş., Erbay L. G., ZAYMAN E. P., OTLU O., KARABULUT A. B., KARTALCI G.

TURK PSIKIYATRI DERGISI, cilt.27, sa.3, ss.170-175, 2016 (SSCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5080/u13642
  • Dergi Adı: TURK PSIKIYATRI DERGISI
  • Derginin Tarandığı İndeksler: Social Sciences Citation Index (SSCI), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.170-175
  • Anahtar Kelimeler: Schizophrenia, IL-4, TGF-beta, NF-kappa B, myeloperoxidase, INFLAMMATORY RESPONSE SYSTEM, BIPOLAR DISORDER, PSYCHIATRIC-DISORDERS, IMMUNE-SYSTEM, CYTOKINE ALTERATIONS, CEREBROSPINAL-FLUID, OXIDATIVE STRESS, MAJOR DEPRESSION, GENE-EXPRESSION, GROWTH
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective: Schizophrenia is a chronic psychotic disorder in which genetics and environmental factors such as infection and the corresponding immune response play a role in the etiopathogenesis. The aim of this study was to compare some immune factors such as nuclear factor-kappa B (NF-kappa B) activation, myeloperoxidase (MPO), the anti-inflammatory cytokine interleukin-4 (IL-4), and regulatory cytokine transforming growth factor-beta (TGF-beta) in schizophrenia patients and an age- and gender-matched control group.