IL-4, TGF-beta, NF-kappa B and MPO levels in Patients with Treatment Resistant Schizophrenia

KARTALCI Ş. , Erbay L. G. , ZAYMAN E. P. , OTLU O., KARABULUT A. B. , KARTALCI G.

TURK PSIKIYATRI DERGISI, cilt.27, ss.170-175, 2016 (SSCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 27 Konu: 3
  • Basım Tarihi: 2016
  • Doi Numarası: 10.5080/u13642
  • Dergi Adı: TURK PSIKIYATRI DERGISI
  • Sayfa Sayıları: ss.170-175

Özet

Objective: Schizophrenia is a chronic psychotic disorder in which genetics and environmental factors such as infection and the corresponding immune response play a role in the etiopathogenesis. The aim of this study was to compare some immune factors such as nuclear factor-kappa B (NF-kappa B) activation, myeloperoxidase (MPO), the anti-inflammatory cytokine interleukin-4 (IL-4), and regulatory cytokine transforming growth factor-beta (TGF-beta) in schizophrenia patients and an age- and gender-matched control group.