Three novel mutations in the apolipoprotein E gene in a sample of individuals with type 2 diabetes mellitus


STEPHENS J., Sozen M. M. , WHITTALL R., CASLAKE M., BEDFORD D., ACHARYA J., ...Daha Fazla

CLINICAL CHEMISTRY, cilt.51, ss.119-124, 2005 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 51 Konu: 1
  • Basım Tarihi: 2005
  • Doi Numarası: 10.1373/j.clinchem.2004.040121
  • Dergi Adı: CLINICAL CHEMISTRY
  • Sayfa Sayıları: ss.119-124

Özet

Background: Apolipoprotein E (apoE) is found in association with triglyceride-rich lipoproteins and is the ligand for the removal of these particles from the plasma. Genetic variations in exon 4 lead to three common gene variants: E2, E3, and E4.