Investigation of Regenerative Effects of Theranekron® and Misoprostol after Partial Hepatectomy in Rats


Yılmaz İ., Kanat B. H., Yıldız A., Bilgiç Y., Berk A., Uyumlu A. B., ...Daha Fazla

J Transl Med Transplant Res, cilt.2, sa.3, ss.1-9, 2023 (Hakemli Dergi)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 2 Sayı: 3
  • Basım Tarihi: 2023
  • Doi Numarası: 10.47363/jtmtr/2023(2)109
  • Dergi Adı: J Transl Med Transplant Res
  • Derginin Tarandığı İndeksler: Other Indexes
  • Sayfa Sayıları: ss.1-9
  • İnönü Üniversitesi Adresli: Evet

Özet

 In the present study we were aimed to investigate/compare regenerative effects of Theranekron® (TC) and Misoprostol (MS) after Partial Hepatectomy (PH) in rats. This study was conducted in 38 rats, they were divided in to 5 groups and 7 days study periot. When considering biochemical and histopathological results; we were seen that after PH 7 days duration was not sufficient and also at least 10 days periot may be necessary. Although some literatures were reported about positive effects of TC and MS on epithelial growing, we have not seen that they have not any positive effect on liver regeneration. In the future -at different doses and durations- these may be found effective