N-Heterocyclic carbene-palladium catalysts for the direct arylation of pyrrole derivatives with aryl chlorides


ÖZDEMİR İ. , GÜRBÜZ N. , KALOGLU N., DOGAN O., KALOĞLU M. , BRUNEAU C., ...Daha Fazla

BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, cilt.9, ss.303-312, 2013 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 9
  • Basım Tarihi: 2013
  • Doi Numarası: 10.3762/bjoc.9.35
  • Dergi Adı: BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY
  • Sayfa Sayıları: ss.303-312

Özet

New Pd-NHC complexes have been synthesized and employed for palladium-catalyzed direct arylation of pyrrole derivatives by using electron-deficient aryl chlorides as coupling partners. The desired coupling products were obtained in moderate to good yields by using 1 mol % of these air-stable palladium complexes. This is an advantage compared to the procedures employing air-sensitive phosphines, which have been previously shown to promote the coupling of aryl chlorides with heteroarenes.