Hypothyroidism masquerading as depression: The role of noncompliance


Sevinc A., Savli H.

JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION, cilt.96, ss.379-382, 2004 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 96 Konu: 3
  • Basım Tarihi: 2004
  • Dergi Adı: JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION
  • Sayfa Sayıları: ss.379-382

Özet

Compliance with prescribed medication is an important but complex issue which is incompletely understood, Depression is also a factor that can lead to noncompliance. A 30-year-old lady was seen in the outpatient clinic with complaints of palpitations and tremor. Her medical history revealed a subtotal thyroidectomy for multinodular goiter five years earlier. During a period of depression, she stopped taking levothyroxine for 45 days. Discontinuation of therapy worsened her depression. At her visit, the dosage of levothyroxine was increased, and the symptoms of depression improved. However, increasing the dosage of thyroid supplement resulted in a hyperthyroid state. The role of depression on noncompliance is also discussed.