Synthesis and Characterization of Ag(I)NHC Complexes Bearing Triflouromethylthioether Group

Yavuz K., Aktaş A., Gök Y.

5TH INTERNATIONAL EURASIAN CONFERENCE ON BIOLOGICAL AND CHEMICAL SCIENCES, Ankara, Türkiye, 23 - 25 Kasım 2022, ss.11

  • Yayın Türü: Bildiri / Özet Bildiri
  • Basıldığı Şehir: Ankara
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.11
  • İnönü Üniversitesi Adresli: Evet

Özet

The organic ligands play a significant role in biological activity by coordinating with the silver metal core. N-heterocyclic carbenes (NHCs) rank among the most significant organic ligands among them. The applications of transition metal complexes containing NHC ligands (M-NHC) are numerous. Applications of Ag-NHC complexes made from these substances for biological activity have attracted interest. Additionally, investigations on the use of Ag-NHC complexes for biological activity have only lately begun [1], and their number is growing daily. Long ago, silver's potential uses in medicine were identified [2]. Silver nitrate and silver sulfonamides are the most widely used silver compounds [1]. Nowadays, it is recognized that the majority of organisms become resistant to antibiotics. Therefore, scientists have worked to create new, more powerful, and multimodal substitutes that have the least negative effects of antibiotics on the human body [3]. Silver has been demonstrated to have widespread activity against antibiotics, even those resistant to lethal bacteria, at the clinical stage [4]. Recent research has shown that silver complexes are less hazardous to humans than other metal complexes, making them suitable antibacterial agents [5].