Evaluation of retinal nerve fibre layer, ganglion cell layer and choroidal thickness with optical coherence tomography in migraine patients: a case-control study

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GUNES A., Karadag A. S., Yazgan S., Celik H. U., Simsek A.

CLINICAL AND EXPERIMENTAL OPTOMETRY, cilt.101, sa.1, ss.109-115, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 101 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1111/cxo.12585
  • Dergi Adı: CLINICAL AND EXPERIMENTAL OPTOMETRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.109-115
  • Anahtar Kelimeler: choroidal thickness, chronic migraine, optical coherence tomography, retinal ganglion cell layer, retinal nerve fibre layer, REPRODUCIBILITY, VASOSPASM
  • İnönü Üniversitesi Adresli: Hayır

Özet

BackgroundEvaluation of retinal nerve fibre layer (RNFL), ganglion cell layer (GCL) and choroidal thickness (CT) with optical coherence tomography (OCT) in chronic migraine patients, to compare with healthy controls.

Abstract

BACKGROUND:

Evaluation of retinal nerve fibre layer (RNFL), ganglion cell layer (GCL) and choroidal thickness (CT) with optical coherence tomography (OCT) in chronic migraine patients, to compare with healthy controls.

MATERIAL AND METHOD:

Ninety-four eyes of 47 chronic migraine patients (Group 1) and 68 eyes of 34 healthy individuals (Group 2) were included in this prospective case-control study. The right and left eyes were separately evaluated. Mean peripapillary RNFL thicknesses, mean GCL measured from superior and inferior quadrants, and mean CT were measured at three different regions (central, 500 μm nasal and temporal region of the fovea).

RESULTS:

There was no statistically significant differences in RNFL between the two groups (p > 0.05), while CT values were significantly higher and GCL values were significantly lower in chronic migraine groups (p < 0.05). There were no statistically significant differences between migraine duration, frequency and length of attacks, presence of aura, relation to menstrual cycle, white matter lesions in cranial magnetic resonance imaging and RNFL, GCL and CT (p > 0.05).

DISCUSSION:

In this study, we observed chronic migraine disease does not have any effect on peripapillary RNFL thickness; however, increases in CT and decreases in GCL thickness were observed in migraine patients.

© 2017 Optometry Australia.

KEYWORDS:

choroidal thickness; chronic migraine; optical coherence tomography; retinal ganglion cell layer; retinal nerve fibre layer