Investigation of the effect of lacosamide on renal function: A 5-Year retrospective cohort study

ADIGÜZEL A.

ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, cilt.13, ss.11-15, 2022 (ESCI) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 13
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4328/acam.21059
  • Dergi Adı: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
  • Sayfa Sayıları: ss.11-15
  • Anahtar Kelimeler: Lacosamide, Antiepileptic Drugs, GFR, Sodium Channel Blocker, Seizure, REFRACTORY EPILEPSY, TOLERABILITY, SAFETY, RISK
  • İnönü Üniversitesi Adresli: Evet

Özet

Aim: Lacosamide, a third-generation antiepileptic drug, is used as adjunctive treatment of partial-onset seizures. It is mainly eliminated through the kidneys. The drug acts by enhancing the slow inactivation of voltage-gated sodium channels. The aim of this study was to investigate the long-term effects of lacosamide on renal function.