Investigation of the effect of lacosamide on renal function: A 5-Year retrospective cohort study
ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, vol.13, pp.11-15, 2022 (ESCI)
- Publication Type: Article / Article
- Volume: 13
- Publication Date: 2022
- Doi Number: 10.4328/acam.21059
- Journal Name: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
- Journal Indexes: Emerging Sources Citation Index (ESCI)
- Page Numbers: pp.11-15
- Keywords: Lacosamide, Antiepileptic Drugs, GFR, Sodium Channel Blocker, Seizure, REFRACTORY EPILEPSY, TOLERABILITY, SAFETY, RISK
- Inonu University Affiliated: Yes
Abstract
Aim: Lacosamide, a third-generation antiepileptic drug, is used as adjunctive treatment of partial-onset seizures. It is mainly eliminated through the kidneys. The drug acts by enhancing the slow inactivation of voltage-gated sodium channels. The aim of this study was to investigate the long-term effects of lacosamide on renal function.