Investigation of the effect of lacosamide on renal function: A 5-Year retrospective cohort study
ANNALS OF CLINICAL AND ANALYTICAL MEDICINE, cilt.13, ss.11-15, 2022 (ESCI)
- Yayın Türü: Makale / Tam Makale
- Cilt numarası: 13
- Basım Tarihi: 2022
- Doi Numarası: 10.4328/acam.21059
- Dergi Adı: ANNALS OF CLINICAL AND ANALYTICAL MEDICINE
- Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI)
- Sayfa Sayıları: ss.11-15
- Anahtar Kelimeler: Lacosamide, Antiepileptic Drugs, GFR, Sodium Channel Blocker, Seizure, REFRACTORY EPILEPSY, TOLERABILITY, SAFETY, RISK
- İnönü Üniversitesi Adresli: Evet
Özet
Aim: Lacosamide, a third-generation antiepileptic drug, is used as adjunctive treatment of partial-onset seizures. It is mainly eliminated through the kidneys. The drug acts by enhancing the slow inactivation of voltage-gated sodium channels. The aim of this study was to investigate the long-term effects of lacosamide on renal function.