Neutrophil superoxide anion production, and CAT and GSSGR activity in patients with tuberculosis


Duzova H. , ASMA D. , EMRE M.

MICROBIOLOGICA, cilt.26, ss.289-298, 2003 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 26 Konu: 3
  • Basım Tarihi: 2003
  • Dergi Adı: MICROBIOLOGICA
  • Sayfa Sayıları: ss.289-298

Özet

Tuberculosis (TB) is a chronic infection disease caused by Mycobacterium tuberculosis (MTB), as an intracellular pathogen. Various cytokines (TNF-alpha, IL's,GSF etc.) and other factors play important preventing roles and are secreted during the infection. It may cause changes in the metabolism of neutrophils. Production of superoxide anion and antioxidative enzymes activities, such as glutathione reductase (GSSGR) and catalase (CAT) may be changed during MTB infection in the host.