Melatonin administration prevents the nephrotoxicity induced by gentamicin

Ozbek E., Turkoz Y., Sahna E., Ozugurlu F., Mizrak B., Ozbek M.

BJU INTERNATIONAL, cilt.85, sa.6, ss.742-746, 2000 (SCI-Expanded, Scopus)

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 85 Sayı: 6
  • Basım Tarihi: 2000
  • Doi Numarası: 10.1046/j.1464-410x.2000.00531.x
  • Dergi Adı: BJU INTERNATIONAL
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.742-746
  • Anahtar Kelimeler: gentamicin, nephrotoxicity, melatonin, tubular necrosis, antioxidant enzyme, NEUROHORMONE MELATONIN, SUPEROXIDE-DISMUTASE, ANTIOXIDANT ENZYMES, LIPID-PEROXIDATION, GENE-EXPRESSION, RENAL-FAILURE, LUNG INJURY, ADRIAMYCIN, RATS, EXCITOTOXICITY
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective To investigate the effect of melatonin on the antioxidant enzyme activity and renal tubular necrosis induced by gentamicin.