Prevalence of Familial Mediterranean Fever in Children with Cryptogenic Cirrhosis

VAROL F. İ., TABEL Y., YOLOĞLU S., YEŞİLADA E.

JOURNAL OF TROPICAL PEDIATRICS, vol.67, no.3, 2021 (SCI-Expanded) identifier identifier

  • Publication Type: Article / Article
  • Volume: 67 Issue: 3
  • Publication Date: 2021
  • Doi Number: 10.1093/tropej/fmab019
  • Journal Name: JOURNAL OF TROPICAL PEDIATRICS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, CAB Abstracts, CINAHL, EMBASE, Index Islamicus, MEDLINE, Veterinary Science Database
  • Keywords: children, chronic liver disease, cryptogenic cirrhosis, familial Mediterranean fever, LIVER, BIOMARKERS
  • Inonu University Affiliated: Yes

Abstract

Background: Familial Mediterranean fever (FMF) is an autoinflammatory disease characterized by abdominal and chest pain and recurrent fever due to inflammation in the serosal membranes such as peritoneum, pleura and synovia. In FMF, recurrent inflammatory cytokine production may lead to cirrhosis. The aim of this study was to determine the prevalence of FMF in children with cryptogenic cirrhosis and it was found to be high, to add FMF among the etiological causes of cirrhosis.