Akademik Veri Yönetim Sistemi
International Journal of Clinical Images and Medical Reviews, cilt.1, sa.1, ss.1-3, 2022 (Hakemli Dergi)
Background: Multiple myeloma (MM) and Non-hodgkin lymphoma (NHL) are frequently seen among hematological malignancies.
Autologous hematopoietic stem cell transplantation is a treatment
approach that is frequently used in patients with MM who develop
consolidation therapy and in patients with non-hodgkin lymphoma
who develop recurrence after standard treatments.
Materials and Methods: After the approval of the scientific research
projects coordination unit (BAP) of İnönü University in 2017, the
study data were collected. Project ID: 698. CD34+ cells were harvested from patients undergoing autologue stem cell transplantation after the mobilization regimen. Before mobilization, parathyroid hormone and vitamin D levels were measured in the patients.
The relationship between the SPSS statistical program and the current data of the patients was examined.
Result: A total of 77 patients with 28 non-hodgkin lymphoma and
49 multiple myeloma were included in the study. The mean age
of the patients was 55±11 and 55 were male and 22 were female.
Parathormone level of lymphoma patients was identified as 68.8 ±
43.6 pg/mL, Vitamin D level was 7. 68±5.85 ng/mL and CD34+ cell
number was 9.08x106/kg. The relationship between PTH and vitamin D levels or CD34 stem cell number in lymphoma patients
was not statistically significant. Parathormone level of multiple
myeloma patients was identified as 88.36±76.3 pg/mL, Vitamin
D level was 68±ng/mL, and CD34+ cell count was 10.28x106/kg.
The relationship between PTH and vitamin D levels or CD34 stem
cell number in MM patients was not statistically significant.In our
study, it was found that parathyroid hormone and vitamin D levels
with CD34+ cell count were negatively correlated in non-hodgkin
lymphoma and multiple myeloma patients. However, this relationship was not identified statistically significant.