Thiol/Disulfide homeostasis in patients with rheumatoid arthritis

Tuzcu A., Baykara R. A., Omma A., Acet G. K., Dogan E., Cure M. C., ...Daha Fazla

ROMANIAN JOURNAL OF INTERNAL MEDICINE, cilt.57, sa.1, ss.30-36, 2019 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 57 Sayı: 1
  • Basım Tarihi: 2019
  • Doi Numarası: 10.2478/rjim-2018-0025
  • Dergi Adı: ROMANIAN JOURNAL OF INTERNAL MEDICINE
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus
  • Sayfa Sayıları: ss.30-36
  • İnönü Üniversitesi Adresli: Evet

Özet

Background. Oxidative stress may play an important role in rheumatoid arthritis (RA) etiopathogenesis. The thiol group is a very strong antioxidant. In this study, we aimed to investigate the presence of oxidative stress in patients with RA by evaluating thiol/disulfide homeostasis. Material and methods. A total of 50 female RA patients and 50 healthy female controls were included in this study. Thiol and disulfide values were calculated utilizing novel methods.