High Sensitive Voltammetric Gentamicin Sensor using Poly (3-thiophenecarboxylic acid-co-3-methylthiophene) Modified Glassy Carbon Electrode

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Burc M., Duran S. T., Güngör Ö., Köytepe S.

ELECTROANALYSIS, cilt.34, sa.7, ss.1212-1226, 2022 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 7
  • Basım Tarihi: 2022
  • Doi Numarası: 10.1002/elan.202100630
  • Dergi Adı: ELECTROANALYSIS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.1212-1226
  • Anahtar Kelimeler: 3-methylthiophene, 3-thiophenecarboxylic acid, Copolymer, Gentamicin, Square wave voltammetry, VETERINARY DRUG RESIDUES, PHARMACEUTICAL-PREPARATIONS, C COMPONENTS, PHARMACOKINETICS, ANTIBIOTICS, EXCRETION, CURCUMIN, SULFATE
  • İnönü Üniversitesi Adresli: Evet

Özet

For the determination of gentamicin in biomedical applications, sensitive, fast and low cost voltammetric sensor has been developed. Prepared sensor was succecfully used for determination of gentamicine in synthetic urine samples with different voltammetric measurement methods. Firstly, glassy carbon electrode was modified using cyclic voltammetry technique by electropolymerization of 3-thiophenecarboxylic acid and 3-methylthiophene. Then, optimization of the electrochemical parameters was carried out for modifed electrode. With this modified electrode, gentamicin determination was performed in the linear range of 0.05-4.00 mM. The correlation coefficient, limit of detection and limit of quantitation were calculated as 0.9999, 0.039 mM and 0.129 mM, respectively.