Polyenylphosphatidylcholine pretreatment ameliorates ischemic acute renal injury in rats.

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Demirbilek S., Karaman A., Baykarabulut A., Akin M., Gurunluoglu K., Turkmen E., ...Daha Fazla

International journal of urology : official journal of the Japanese Urological Association, cilt.13, sa.6, ss.747-53, 2006 (SCI-Expanded)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 13 Sayı: 6
• Basım Tarihi: 2006
• Doi Numarası: 10.1111/j.1442-2042.2006.01397.x
• Dergi Adı: International journal of urology : official journal of the Japanese Urological Association
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.747-53
• Anahtar Kelimeler: ischemia reperfusion, kidney, neutrophil infiltration, nuclear factor kappa beta, oxidative stress, polyenylphosphatidylcholine, NF-KAPPA-B, REPERFUSION INJURY, ISCHEMIA/REPERFUSION INJURY, OXIDATIVE STRESS, POLYUNSATURATED PHOSPHATIDYLCHOLINE, FREE-RADICALS, ANTIOXIDANT, FAILURE, DAMAGE, ALPHA
• İnönü Üniversitesi Adresli: Evet

Özet

Aim: Polyenylphosphatidycholine has been demonstrated to have antioxidant, cytoprotective and anti-inflammatory effects. Whether polyenylphosphatidycholine pretreatment affects ischemia/reperfusion-induced renal damage in vivo is not known and was investigated here in rats.