Polyimides as dopamine selective membrane were prepared from 4,4'-diaminodicyclohexyl-methane and different dianhydrides. The chemical structure and thermal properties of these polyimides were examined. For the voltammetric sensor applications, polyimides exhibited suitable glass transition temperature (T-g), high thermal stability, and good adhesive properties. Moreover, polyimides were coated onto Pt electrode surface for the preparation of dopamine selective electrodes. Electrochemically dopamine responses of polyimide-coated electrodes were examined by differential pulse voltammetry. The sensor characteristics such as sensitivity, linearity, selectivity, response time, and stability of the prepared sensors have been determined. Prepared polyimide-coated electrodes can be used for selective and sensitive dopamine detection.