Ghrelin is present in teeth

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Aydin S., OZERCAN I. H., Geckil H., DAGLI F., AYDIN S., KUMRU S., ...Daha Fazla

JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY, cilt.40, sa.3, ss.368-372, 2007 (SCI-Expanded, Scopus)

• Yayın Türü: Makale / Tam Makale
• Cilt numarası: 40 Sayı: 3
• Basım Tarihi: 2007
• Doi Numarası: 10.5483/bmbrep.2007.40.3.368
• Dergi Adı: JOURNAL OF BIOCHEMISTRY AND MOLECULAR BIOLOGY
• Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
• Sayfa Sayıları: ss.368-372
• İnönü Üniversitesi Adresli: Evet

Özet

Ghrelin belongs to the family of a gut-brain hormone that promotes food intake and controls energy balance. Recently, it has also been shown to regulate bone formation directly. Dental tissue shares several functional, developmental and anatomical similarities with bone, and in the present study we have investigated the presence of ghrelin in 44 human teeth using immunocytochemistry and radioimmunoassay. Both methods showed that the hormone is present in canines and molars, mainly in the odontoblasts but also in the pulp. Ghrelin could potentially play interesting physiological roles in teeth.