Ecstasy induced acute hepatic failure. Case reports

ATAYAN Y., CAGIN Y. F., ERDOĞAN M. A., HARPUTLUOĞLU M. M. M., BİLGİÇ Y.

ACTA GASTRO-ENTEROLOGICA BELGICA, cilt.78, sa.1, ss.53-55, 2015 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 78 Sayı: 1
  • Basım Tarihi: 2015
  • Dergi Adı: ACTA GASTRO-ENTEROLOGICA BELGICA
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED)
  • Sayfa Sayıları: ss.53-55
  • Anahtar Kelimeler: acute hepatic failure, exctasy, LIVER-TRANSPLANTATION, MDMA, HEPATOTOXICITY, INGESTION, 3,4-METHYLENEDIOXYAMPHETAMINE, MECHANISMS, DEATHS, CYP2D6, DRUGS, RAT
  • İnönü Üniversitesi Adresli: Evet

Özet

3,4-methylenedioxymethamphetamine (MDMA), an amphetamine derivative known as ecstasy, has stimulating and hallucinogenic properties. It has become a substance that is widely used especially by young people. Hepatotoxicity is one of the rare side effects of this substance and can be fatal. Ecstasy-induced fulminant hepatitis has been reported in case reports. The clinical course and the prognosis of the cases may differ. In this article, two cases in whom ecstasy-induced fulminant hepatic failure had developed and who were treated with liver transplantation, and one case which recovered with treatment, have been presented.