Effects of various sodium selenite concentrations on some biochemical and hematological parameters of rainbow trout (Oncorhynchus mykiss)

Orun I., Ates B., Selamoglu Z., Yazlak H., Ozturk E., Yilmaz İ.

FRESENIUS ENVIRONMENTAL BULLETIN, cilt.14, sa.1, ss.18-22, 2005 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 1
  • Basım Tarihi: 2005
  • Dergi Adı: FRESENIUS ENVIRONMENTAL BULLETIN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.18-22
  • Anahtar Kelimeler: selenium, Oncorhynchus mykiss, superoxide dismutase, glutathione peroxidase, malondialdehyde, hematological parameters, FISH, BLOOD, EXPOSURE, CADMIUM, COPPER, LIVER
  • İnönü Üniversitesi Adresli: Evet

Özet

In this study the activity of selenium-dependent glutathione peroxidase (Se-GSH-Px) and the levels of superoxide dismutase (SOD) and malondialdehyde (MA) of rainbow trouts exposed to various concentrations of selenium were determined. Furthermore, the hematological parameters from blood tissue were studied. Although, Se-GSH-Px activity generally increased in all groups for brain, heart and spleen tissues with respect to the control group, the only statistically significant difference (p<0.05) was found in liver tissues of trouts exposed to 4 and 6 ppm sodium selenite (SS). The SOD levels of spleen, heart, liver and brain tissues of 2 and 4 ppm SS-treated fish were also significantly higher than those of control group animals (p<0.05). The MDA values, an indicator for oxidative damage in the cell, were lower in all tissues with regard to control. Furthermore, the erythrocyte number, hemoglobin amount and hematocrit value of SS-treated rainbow trouts were significantly lower than that of control animals (p<0.05). The results show that SS has an important effect on the antioxidative defense at 2 and 4 ppm levels, whereas a 6 ppm dosage appears to be lethal for rainbow trouts.