Relationship between nucleotide-binding oligomerization domain-containing protein 2 variants and severity of acute pancreatitis.

Harputluoglu M. M. M. , Ozbek M., Demirel U., Otlu B., Yener O., Gursoy N. C. , ...Daha Fazla

Acta gastro-enterologica Belgica, cilt.82, ss.285-290, 2019 (SCI Expanded İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 82 Konu: 2
  • Basım Tarihi: 2019
  • Dergi Adı: Acta gastro-enterologica Belgica
  • Sayfa Sayıları: ss.285-290


Background and aim : Intestinal bat tier dysfunction has been implicated in the development of infectious complications of acute pancreatitis. Nucleotide-Binding Oligomerization Domain- Containing Protein 2 (NOD2) plays an important role in the proper functioning of intestinal defense mechanisms. Here, we investigated the frequency of NOD2 variants in patients with mild and severe acute pancreatitis.