Acrylamide applied during pregnancy causes the neurotoxic effect by lowering BDNF levels in the fetal brain

Erdemli, MEHMET; Aladag, M.; ALTINÖZ, EYÜP; Demirtas, Sezin; TÜRKÖZ, YUSUF; Yigitcan, BİRGÜL; GÖZÜKARA BAĞ, HARİKA

doi:10.1016/j.ntt.2018.03.005

Acrylamide applied during pregnancy causes the neurotoxic effect by lowering BDNF levels in the fetal brain

Erdemli M. E., Aladag M. A., ALTINÖZ E., Demirtas S., TÜRKÖZ Y., Yigitcan B., ...Daha Fazla

NEUROTOXICOLOGY AND TERATOLOGY, cilt.67, ss.37-43, 2018 (SCI-Expanded, Scopus)

Yayın Türü: Makale / Tam Makale
Cilt numarası: 67
Basım Tarihi: 2018
Doi Numarası: 10.1016/j.ntt.2018.03.005
Dergi Adı: NEUROTOXICOLOGY AND TERATOLOGY
Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
Sayfa Sayıları: ss.37-43
Anahtar Kelimeler: Acrylamide, Oxidative stress, N-acetylcysteine, Fetal brain development, Brain-derived neurotrophic factor, N-ACETYLCYSTEINE, NEUROTROPHIC FACTOR, DIETARY-INTAKE, SUPPLEMENTATION, NEUROPROTECTION, NEUROGENESIS, EXPOSURE, CELLS, ACID, RATS
İnönü Üniversitesi Adresli: Evet

Özet

Objectives: The aim of this study is to elucidate the possible mechanism of neurotoxic effect of acrylamide (AA) applied during pregnancy on fetal brain development and to show the effect of N-acetylcysteine (NAC) on AA toxicity.