Acrylamide applied during pregnancy causes the neurotoxic effect by lowering BDNF levels in the fetal brain

Erdemli M. E., Aladag M. A., ALTINÖZ E., Demirtas S., TÜRKÖZ Y., Yigitcan B., ...Daha Fazla

NEUROTOXICOLOGY AND TERATOLOGY, cilt.67, ss.37-43, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 67
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.ntt.2018.03.005
  • Dergi Adı: NEUROTOXICOLOGY AND TERATOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.37-43
  • Anahtar Kelimeler: Acrylamide, Oxidative stress, N-acetylcysteine, Fetal brain development, Brain-derived neurotrophic factor, N-ACETYLCYSTEINE, NEUROTROPHIC FACTOR, DIETARY-INTAKE, SUPPLEMENTATION, NEUROPROTECTION, NEUROGENESIS, EXPOSURE, CELLS, ACID, RATS
  • İnönü Üniversitesi Adresli: Evet

Özet

Objectives: The aim of this study is to elucidate the possible mechanism of neurotoxic effect of acrylamide (AA) applied during pregnancy on fetal brain development and to show the effect of N-acetylcysteine (NAC) on AA toxicity.