Akademik Veri Yönetim Sistemi
5th International Organic Chemistry Congress,, Malatya, Türkiye, 14 - 17 Ekim 2021, ss.39
Among N-heterocyclic compounds, imidazoles and benzimidazoles are very important compounds with their interesting
framework. These compounds are mostly found in alkaloids and show quite good biological activities as antimicrobial,
antitumor, antiviral, anti-inflammatory and enzyme inhibition. Omeprazole, proton pump inhibitors, and albendazole, an
antihelmintic, are two examples of many drugs that have imidazole framework in their structures [1-5]. We have synthesized novel 2-methylimidazolium salts; their structures were elucidated by using different spectroscopic
techniques (1H NMR, 13C NMR, and FTIR). The novel 2-methylimidazolium salts 1-5 have been synthesized from the methyl,
benzyl and decyl substituted 2-methylimidazole with 3-bromopropionic acid and 4-(bromomethyl)benzoic acid at 90 °C-110
°C for 24 h. The novel 2-methylimidazolium salts were obtained between 60 % and 75 % yield.