Cerebrospinal Fluid Dynamics in Patients with Multiple Sclerosis: The Role of Phase-Contrast MRI in the Differential Diagnosis of Active and Chronic Disease


ÖNER S., KAHRAMAN A., Ozcan C., Ozdemir Z., Unlu S., KAMIŞLI Ö., ...Daha Fazla

KOREAN JOURNAL OF RADIOLOGY, cilt.19, sa.1, ss.72-78, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 1
  • Basım Tarihi: 2018
  • Doi Numarası: 10.3348/kjr.2018.19.1.72
  • Dergi Adı: KOREAN JOURNAL OF RADIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.72-78
  • Anahtar Kelimeler: Cerebrospinal fluid dynamics, Multiple sclerosis, Chronic cerebrospinal venous insufficiency, Phase contrast cine MRI, VENOUS-BLOOD FLOW, MAGNETIC-RESONANCE, MEDICAL PROGRESS, CSF DYNAMICS, INSUFFICIENCY, HEMODYNAMICS, LESIONS, MODEL
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective: Multiple sclerosis (MS) is an inflammatory disease characterized by demyelinating plaques in the white matter. Chronic cerebrospinal venous insufficiency (CCSVI) has been proposed as a new hypothesis for the etiopathogenesis of MS disease. MS-CCSVI includes a significant decrease of cerebrospinal fluid (CSF) flow through the cerebral aqueduct secondary to an impaired venous outflow from the central nervous system. This study aimed to determine whether CSF flow dynamics are affected in MS patients and the contributions to differential diagnosis in active and chronic disease using phase-contrast magnetic resonance imaging (PC-MRI).