5-Nitrobenzimidazole containing Pd(II) catalyzed C-C cross-coupling reactions: The effect of the N-substituent of the benzimidazole structure on catalyst activity


BULDURUN K., ÖZDEMİR İ.

JOURNAL OF MOLECULAR STRUCTURE, vol.1192, pp.172-177, 2019 (Journal Indexed in SCI) identifier identifier

  • Publication Type: Article / Article
  • Volume: 1192
  • Publication Date: 2019
  • Doi Number: 10.1016/j.molstruc.2019.04.101
  • Title of Journal : JOURNAL OF MOLECULAR STRUCTURE
  • Page Numbers: pp.172-177

Abstract

A series of Pd(II) complexes (1a-e) were successfully synthesized by reaction of N-substituted 5-nitrobenzimidazole with [PdCl2(CNCH3)(2)] in toluene under argon reflux condition. Their catalytic activity in the Suzuki-Miyaura and Mizoroki-Heck coupling reactions were investigated. All these complexes were characterized by elemental analysis, H-1 NMR, C-13 NMR and IR spectroscopy. The catalytic activities of N-substituted 5-nitrobenzimidazole palladium (II) complexes were screened in Mizoroki-Heck and Suzuki-Miyaura coupling reactions. The reactions were optimized for the most suitable temperature, solvent and base system. The Pd(II) complexes exhibited good catalytic activity at the Mizoroki-Heck reaction. Additionally, the Suzuki-Miyaura showed relatively excellent activity at the coupling reaction. (C) 2019 Elsevier B.V. All rights reserved.