High expression of CD8 in the tumor microenvironment is associated with PD-1 expression and patient survival in high-grade serous ovarian cancer

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Olmez F., Oglak S. C., Olmez O. F., Akbayir O., Yilmaz E., Akgol S., ...Daha Fazla

TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY, cilt.19, sa.3, ss.246-256, 2022 (ESCI) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4274/tjod.galenos.2022.59558
  • Dergi Adı: TURKISH JOURNAL OF OBSTETRICS AND GYNECOLOGY
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.246-256
  • Anahtar Kelimeler: High-grade serous ovarian cancer, programmed death-1 receptor, tumor-infiltrating lymphocytes, INFILTRATING T-CELLS, PROGNOSTIC-SIGNIFICANCE, NEOADJUVANT CHEMOTHERAPY, FAVORABLE PROGNOSIS, LYMPHOCYTES, DEATH-1, CD103
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective: The current study assesss programmed death-1 (PD-1) receptor expression and CD3, CD4, and CD8 tumor-infiltrating lymphocytes (TILs) in high-grade serous ovarian cancer (HGSOC) and to associate our results with neoadjuvant chemotherapy history and disease prognosis.