Protective Effects of Molsidomine Against Cisplatin-Induced Nephrotoxicity

KARAKOC H. T. E. , Altintas R. , PARLAKPINAR H. , POLAT A., ŞAMDANCI E. , SAGIR M., ...Daha Fazla

ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE, cilt.24, ss.585-593, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 24 Konu: 4
  • Basım Tarihi: 2015
  • Doi Numarası: 10.17219/acem/58970
  • Dergi Adı: ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE
  • Sayfa Sayıları: ss.585-593

Özet

Background. Cisplatin, an effective chemotherapeutic agent, is used for the treatment of several types of cancers. However, cisplatin has some severe side effects such as nephrotoxicity. On the other hand, molsidomine, a NO donor, has anti-oxidative and vasodilator effects.