POTENTIAL PROGNOSTIC ROLE OF IMMUNE SYSTEM ACTIVATION MARKER NEOPTERIN IN PATIENTS WITH TYPE 2 DIABETES

ÜNÜVAR S., tanrıverdi Z., Aslanhan H.

JOURNAL OF MEDICAL BIOCHEMISTRY, cilt.37, sa.4, ss.465-469, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 37 Sayı: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.2478/jomb-2018-0004
  • Dergi Adı: JOURNAL OF MEDICAL BIOCHEMISTRY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.465-469
  • Anahtar Kelimeler: type 2 diabetes, metabolic diseases, neopterin, immune system activation, interferon-gamma, L-ARGININE, MELLITUS, RISK
  • İnönü Üniversitesi Adresli: Evet

Özet

Background: An increase in neopterin concentrations is known in some pathologies due to interferon-gamma (INF-gamma) activation. These include viral and bacterial infections, autoimmune diseases, metabolic diseases, psychiatric disorders, tissue and organ rejections, and different malignancies. The aim of this study was to evaluate the role of neopterin as a prognostic biomarker in type 2 diabetes, which is a metabolic disease with a high worldwide prevalence.