Neutrophil-lymphocyte and Platelet-lymphocyte Ratios among Adolescents with Substance Use Disorder: A Preliminary Study


Karatoprak S., Uzun N., Akinci M. A., Donmez Y. E.

CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE, cilt.19, sa.4, ss.669-676, 2021 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 4
  • Basım Tarihi: 2021
  • Doi Numarası: 10.9758/cpn.2021.19.4.669
  • Dergi Adı: CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, BIOSIS, EMBASE, Psycinfo
  • Sayfa Sayıları: ss.669-676
  • Anahtar Kelimeler: Substance use disorder, Inflammation, Neutrophil, Lymphocyte, Platelet, Adolescents, NEUTROPHIL/LYMPHOCYTE RATIO, INFLAMMATORY RESPONSE, MICROGLIAL ACTIVATION, BIPOLAR DISORDER, HEROIN-ADDICTS, MARKERS, SCHIZOPHRENIA, MAINTENANCE, MINOCYCLINE, SEVERITY
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective: Substance use disorder (SUD) is a serious public health problem affecting both the individual and the society, and substance use-related deaths and disability have been shown to increase gradually. Recent etiologic studies have reported that there is a relation between inflammatory parameters and psychiatric disorders. The neutrophil-lymphocyte ratio (NLR) and platelet-lymphocyte ratio (PLR) used as an indicator of inflammation have been shown to be increased in various psychiatric disorders. In this study, we aimed to investigate the NLR and PLR in adolescents with SUD.