Akademik Veri Yönetim Sistemi
CELIAC DISEASE: ETIOLOGY, DIAGNOSIS AND TREATMENT, ss.147-171, 2009 (SCI-Expanded)
Celiac disease (CD) once was recognized as a gastrointestinal disease is now known as a disorder with a wide spectrum of signs and symptoms, including dermatological manifestations. A variety of dermatological changes may occur during the course of CD, including desquamating or psoriatic dermatitis, pigmentation, hair and nail abnormalities, as well as the associated specific lesion of dermatitis herpetiformis. Mucocutaneous conditions associated with CD may be classified into two main etiological groups: (1) Autoimmune or immunologically mediated conditions; (2) conditions that result from the complications of malabsorption. However at present the data are not homogeneous and most of the evidence for the association between CD and skin disorders is based on individual cases, making it difficult to draw definitive conclusions on this topic. Sometimes cutaneous symptoms may be the only symptoms of CD, thus dermatologists should recognize the most common dermal and other manifestations of CD, so as to initiate appropriate screening investigations where indicated. In that chapter dermatological disorders associated with CD are discussed.