1,3-Dioxane Functionalized Pd-PEPPSI Catalyst for Direct Arylation of Heteroaromatics

DOĞAN ULU Ö.

JOURNAL OF MOLECULAR STRUCTURE, cilt.1246, 2021 (SCI-Expanded, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 1246
  • Basım Tarihi: 2021
  • Doi Numarası: 10.1016/j.molstruc.2021.131202
  • Dergi Adı: JOURNAL OF MOLECULAR STRUCTURE
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core, INSPEC
  • Anahtar Kelimeler: N-Heterocyclic carbene, Direct arylation, Palladium, PEPPSI-complex, HETEROCYCLIC CARBENE COMPLEXES, COUPLING REACTION, NHC COMPLEXES, (HETERO)ARYLATION, PRECATALYST, ACTIVATION
  • İnönü Üniversitesi Adresli: Evet

Özet

A series of benzimidazolium salts (1a-d) and their Pd-PEPPSI complexes (pyridine-enhanced precatalyst preparation, stabilization, and initiation) (2a-d) were prepared to catalyze the direct arylation of heteroaromatics (2-acetylthiophene and 2-furaldehyde) with various aryl bromides. The structures of all isolated compounds were elucidated based on spectroscopic methods (H-1 and C-13 NMR, FT-IR and LC-MS spectroscopy). Under optimized reaction conditions, C5-arylated products were obtained in moderate to excellent yields in the direct arylation of heteroaromatics. (C) 2021 Elsevier B.V. All rights reserved.