Accelerated atherosclerosis in haemodialysis patients; correlation of endothelial function with oxidative DNA damage

Kaya Y., Ari E., Demir H., Soylemez N., ÇEBİ A., Alp H. H., ...Daha Fazla

NEPHROLOGY DIALYSIS TRANSPLANTATION, cilt.27, sa.3, ss.1164-1169, 2012 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 27 Sayı: 3
  • Basım Tarihi: 2012
  • Doi Numarası: 10.1093/ndt/gfr443
  • Dergi Adı: NEPHROLOGY DIALYSIS TRANSPLANTATION
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.1164-1169
  • Anahtar Kelimeler: endothelial dysfunction, haemodialysis, oxidative DNA damage, CARDIOVASCULAR RISK-FACTORS, CHRONIC-RENAL-FAILURE, PROTEIN PRODUCTS, OXIDANT STRESS, LEUKOCYTE DNA, MALONDIALDEHYDE, DYSFUNCTION, CAPACITY, CHILDREN, LIPIDS
  • İnönü Üniversitesi Adresli: Evet

Özet

Background. Accelerated atherosclerosis is the major cause of mortality in patients on chronic haemodialysis (HD). The aim of this study was to evaluate the relationship between oxidative DNA damage [8-hydroxy-2'-deoxyguanosine/deoxyguanosine ratio (8-OHdG/dG ratio)], oxidative stress biomarkers and endothelial function in HD patients as an indicator of atherosclerosis.