CHANGES IN TYROSINE HYDROXYLASE ACTIVITY, ADRENOMEDULLIN (ADM) AND TOTAL RNA LEVELS BY TREATMENT OF ORGANOSELENIUM COMPOUNDS IN RAT HYPOTHALAMUS EXPOSED TO 7,12-DIMETHYLBENZANTHRACENE (DMBA)

ÖZDEMİR İ., TALAS Z. S., GÖK Y., ATEŞ B., Yılmaz İ.

FRESENIUS ENVIRONMENTAL BULLETIN, cilt.19, sa.4A, ss.664-668, 2010 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 19 Sayı: 4A
  • Basım Tarihi: 2010
  • Dergi Adı: FRESENIUS ENVIRONMENTAL BULLETIN
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.664-668
  • Anahtar Kelimeler: Tyrosine hydroxylase, adrenomedullin, hypothalamus, synthetic organoselenium compounds, DMBA, HEMATOLOGICAL PARAMETERS, HYPOTENSIVE PEPTIDE, GENE-EXPRESSION, SELENIUM, MODULATION, EXERCISE, STRESS, BRAIN, COLD, STEP
  • İnönü Üniversitesi Adresli: Evet

Özet

The effects of synthetic organoselenium compounds (Se I and Se II) on the activity of tyrosine hydroxylase (TH), the rate-limiting enzyme in catecholamine synthesis as well as adrenomedullin (ADM) and total RNA levels were determined in the hypothalamus of adult rats exposed to DMBA (7,12-dimethylbenz[a]anthracene).