Ameliorative effects of aminoguanidine on rat aorta in Streptozotocin-induced diabetes and evaluation of alpha-SMA expression

ELBE H., VARDI N., ORMAN D., TASLIDERE E., YILDIZ A.

ANATOLIAN JOURNAL OF CARDIOLOGY, cilt.14, sa.8, ss.679-684, 2014 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 14 Sayı: 8
  • Basım Tarihi: 2014
  • Doi Numarası: 10.5152/akd.2014.5047
  • Dergi Adı: ANATOLIAN JOURNAL OF CARDIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CINAHL, EMBASE, MEDLINE, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.679-684
  • Anahtar Kelimeler: diabetes, aminoguanidine, alpha-smooth muscle actin, nitric oxide, aorta, rat, SMOOTH-MUSCLE-CELLS, INTIMA-MEDIA THICKNESS, OXIDATIVE STRESS, LIPID-PEROXIDATION, NITRIC-OXIDE, ATHEROSCLEROSIS, MARKER, GROWTH, PROTECTS, LESIONS
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective: Diabetes mellitus is one of the chronic metabolic diseases which is characterized by microvascular and macrovascular complications. This study was designed to investigate the improving the effects of amnioguanidine on aortic damage in a streptozotocin (STZ) induced diabetic rat model.