Akademik Veri Yönetim Sistemi
INTERNATIONAL CONGRESS ON MODERN SCIENCES-IV "GLOBAL PROSPECTS FOR MULTIDISCIPLINARY RESEARCH AND EDUCATION", Çirçik, Özbekistan, 7 - 10 Nisan 2025, ss.848-849, (Özet Bildiri)
Echinophora tenuifolia subsp. sibthorpiana is an aromatic plant belonging to the Apiaceae family, traditionally used for various medicinal purposes. In Turkey, it is commonly utilized as a spice and has been traditionally employed for its digestive, ulcer-healing, and wound-healing properties. However, there is limited scientific data regarding its phytochemical composition and pharmacological potential. This study aims to comprehensively evaluate its bioactive compounds and antioxidant capacity. The total phenolic and flavonoid content of the plant was determined using spectrophotometric methods, while its antioxidant potential was analyzed through DPPH, ABTS, and CUPRAC assays. The results indicated that the total phenolic content in the methanol-water-HCl solution was 291.96 ± 0.32 µg PEs/mg, while the total flavonoid content was 317.05 ± 1.21 µg QEs/mg. The antioxidant capacity assessments revealed a DPPH IC50 value of 2.86 ± 0.13 µg/mL, ABTS IC50 value of 4.34 ± 0.12 µg/mL, and CUPRAC A0.5 value of 8.26 ± 0.12 µg/mL. LC-MS/MS analysis identified significant amounts of quinic acid (173,925 µg), chlorogenic acid (100,745 µg), rutin (338,154 µg), isoquercitrin (121,588 µg), and hesperidin (194,868 µg). These bioactive compounds contribute to the plant’s antioxidant capacity, reinforcing its pharmacological potential. The findings suggest that E. tenuifolia subsp. sibthorpiana exhibits high antioxidant activity, and its phenolic components warrant further biological investigation. Further pharmacological and clinical studies are required to gain deeper insights into the plant’s potential therapeutic applications.