A COMPARISON OF SATB2 EXPRESSION RESULTS WITH CK20 AND CDX2 IN METASTATIC COLORECTAL CARCINOMA CASES


Bozdag Z., AKATLI A. N.

ACTA MEDICA MEDITERRANEA, cilt.35, ss.1067-1071, 2019 (SCI İndekslerine Giren Dergi) identifier identifier

  • Cilt numarası: 35 Konu: 2
  • Basım Tarihi: 2019
  • Doi Numarası: 10.19193/0393-6384_2019_2_163
  • Dergi Adı: ACTA MEDICA MEDITERRANEA
  • Sayfa Sayıları: ss.1067-1071

Özet

Introduction: SATB2 (The special AT-rich sequence-binding protein 2) is the new DNA binding protein and nuclear transcrip-tion factor. In normal epithelial tissues, the SATB2 protein is specifically expressed in the nuclei of the lower gastrointestinal (GI) tract epithelial cells. The elective expression of SATB2 in the lower GI tract implies that it can be used as a diagnostic marker for metastatic colorectal carcinoma (CRC).