Developmental and lethal effects of glyphosate and a glyphosate-based product on Xenopus laevis embryos and tadpoles


ÖZHAN TURHAN D. , GÜNGÖRDÜ A. , ÖZMEN M.

BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY, cilt.104, ss.173-179, 2020 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 104 Konu: 2
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1007/s00128-019-02774-z
  • Dergi Adı: BULLETIN OF ENVIRONMENTAL CONTAMINATION AND TOXICOLOGY
  • Sayfa Sayıları: ss.173-179

Özet

Effects of pure glyphosate and a glyphosate-based product were evaluated comparatively using two embryonic development stages of Xenopus laevis as model system. When pure glyphosate was applied in pH adjusted media, lethal or developmental effects were not observed at concentrations up to 500 mg L-1. The 96 h LC50 values for the commercial herbicide, in contrast, were 32.1 and 35.1 mg active ingredient L-1 for embryos and tadpoles, respectively. Since pure glyphosate has no effect on the selected biomarkers, it is thought that developmental toxic effects caused by glyphosate-based products are increased mainly due to formulation additives.