Synthesis and antimicrobial activity of electron rich olefin derived cyclic ureas

CETINKAYA B., CETINKAYA E., Kucukbay H., DURMAZ R.

ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, cilt.46, sa.12, ss.1154-1158, 1996 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 46 Sayı: 12
  • Basım Tarihi: 1996
  • Dergi Adı: ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, International Pharmaceutical Abstracts
  • Sayfa Sayıları: ss.1154-1158
  • Anahtar Kelimeler: antibiotics, benzimidazole derivatives, imidazole derivatives, urea derivatives, antimicrobial activity, cyclic, TRANSITION-METAL COMPLEXES, CHEMISTRY
  • İnönü Üniversitesi Adresli: Evet

Özet

Seventeen cyclic ureas containing imidazolidine and benzimidazoline nuclei were synthesised by the reaction of electron-rich olefins with appropriate group 16 elements (O, S, Se, Te). The compounds synthesised were identified by H-1, C-13-NMR, FT-IR and mass spectroscopic techniques and micro analysis. All compounds studied in this work were screened for their in vitro antimicrobial activity against standard strains: Enterococcus faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Escherichia coli (ATCC) 25922) and Pseudomonas aeruginosa (ATCC 27853).