Antifungal activity of organic and organometallic derivatives of benzimidazole and benzothiazole

KÜÇÜKBAY H., Durmaz B.

ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH, cilt.47, sa.5, ss.667-670, 1997 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 47 Sayı: 5
  • Basım Tarihi: 1997
  • Dergi Adı: ARZNEIMITTEL-FORSCHUNG/DRUG RESEARCH
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.667-670
  • Anahtar Kelimeler: antifungal drugs, benzimidazole derivatives, in vitro studies, benzothiazole derivatives, in vitro studies, carbene-rhodium(I) complexes, in vitro studies, carbene-ruthenium(II) complexes, in vitro studies, COMPLEXES
  • İnönü Üniversitesi Adresli: Evet

Özet

Forty organic or organometallic derivatives of benzimidazole and benzothiazole and five rhodium(I) and ruthenium(Ir) complexes were evaluated for their in vitro antifungal activity against Candida albicans. Four of the tested compounds, the rhodium containing compounds 30, 31, 32 and 33, were found effective at the minimum inhibitory concentrations(MICs) between 400-600 mu g/ml.