The study was conducted to evaluate the meaning of life and self-care agency in nursing care given to chronic obstructive pulmonary patients according to the health promotion model, The sample of the study was determined by power analysis and 40 COPD patients were assigned to each group by simple random sampling method. Descriptive Information Form, Life Attitude Profile and Self-care Agency Scale were used to obtain the data. Nursing care was applied by the researcher 3 times in every 2 weeks according to the health promotion model in the houses of the patients in the experimental groups. Number, percentage, mean, standard deviation, dependent samples t-test, independent samples t-test, chi-square and ANOVA were used to analyze the data. It was determined that while posttest mean score of the patients in the Experimental group 1 for Self-care agency scale was 112.70 +/- 29.0; their posttest mean score for Life Attitude Profile was 156.37 +/- 13.5. Posttest mean score of the patients in the Control group 1 for Self-care agency scale was 81.35 +/- 17.7; whereas, their posttest mean score for Life Attitude Profile was 120.50 +/- 31.9. The difference between the posttest mean scores of the groups was statistically significant (p < 0.05). The care applied to the patients with COPD according to health promotion model was found to increase self-care agency and meaning of life of the patients.