Research Information System
Scientific Reports, vol.16, no.1, 2026 (SCI-Expanded, Scopus)
Wagner Grade 3 diabetic foot osteomyelitis is a severe infection involving bone, often requiring a multidisciplinary approach for effective management. While percutaneous bone biopsy is widely recognized as the gold standard for pathogen identification, the addition of percutaneous bactericidal irrigation has not been extensively explored in the literature. This study evaluates a minimally invasive approach combining percutaneous needle culture sampling with Dakins’ solution irrigation in a single session. A retrospective analysis of 31 patients was conducted to assess its feasibility, effectiveness in pathogen identification, and impact on infection control. The most frequently isolated bacterium was Staphylococcus aureus, with no significant correlation between bacterial type and infected bone. Four patients required re-intervention due to persistent symptoms, revealing different bacterial isolates upon re-culture. Significant reductions in CRP levels were observed post-intervention, while WBC changes were not statistically significant. These findings suggest that this combined percutaneous approach may be an effective and minimally invasive strategy for both diagnostic and therapeutic purposes in Wagner Grade 3 osteomyelitis. Further studies with larger sample sizes and extended follow-up are warranted to confirm its long-term benefits.