Estimating the age of Hb G-Coushatta [22(B4)GluAla] mutation by haplotypes of -globin gene cluster in Denizli, Turkey


ÖZTÜRK O. , ARIKAN S., ATALAY A., ATALAY E. Ö.

MOLECULAR GENETICS & GENOMIC MEDICINE, cilt.6, ss.547-554, 2018 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 6 Konu: 4
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1002/mgg3.404
  • Dergi Adı: MOLECULAR GENETICS & GENOMIC MEDICINE
  • Sayfa Sayıları: ss.547-554

Özet

BackgroundHb G-Coushatta variant was reported from various populations' parts of the world such as Thai, Korea, Algeria, Thailand, China, Japan and Turkey. In our study, we aimed to discuss the possible historical relationships of the Hb G-Coushatta mutation with the possible migration routes of the world. For this purpose, associated haplotypes were determined using polymorphic loci in the beta globin gene cluster of hemoglobin G-Coushatta and normal populations in Denizli, Turkey.