Serum Level of ADAMTS4 and ADAMTS8 in Patients with Psoriatic Arthritis
ERCIYES MEDICAL JOURNAL, vol.43, no.1, pp.20-25, 2021 (ESCI, TRDizin)
- Publication Type: Article / Article
- Volume: 43 Issue: 1
- Publication Date: 2021
- Doi Number: 10.14744/etd.2020.65625
- Journal Name: ERCIYES MEDICAL JOURNAL
- Journal Indexes: Emerging Sources Citation Index (ESCI), Academic Search Premier, CAB Abstracts, EMBASE, Veterinary Science Database, Directory of Open Access Journals, TR DİZİN (ULAKBİM)
- Page Numbers: pp.20-25
- Inonu University Affiliated: Yes
Abstract
Objective: Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis. A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) is a large family of proteoglycanase enzymes that show proteolytic activity. The expression levels of ADAMTS proteases in osteoarthritis and rheumatoid arthritis are upregulated. However, their expression levels in PsA patients have not been examined yet. The aim of this study was to determine the serum levels of ADAMTS4 and ADAMTS8 in PsA patients.