Serum Level of ADAMTS4 and ADAMTS8 in Patients with Psoriatic Arthritis


İÇEN TAŞKIN I. , Kandemir S. I. , Nas K., Dagli A. Z.

ERCIYES MEDICAL JOURNAL, vol.43, no.1, pp.20-25, 2021 (Journal Indexed in ESCI) identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 1
  • Publication Date: 2021
  • Doi Number: 10.14744/etd.2020.65625
  • Title of Journal : ERCIYES MEDICAL JOURNAL
  • Page Numbers: pp.20-25

Abstract

Objective: Psoriatic arthritis (PsA) is a chronic inflammatory disease associated with psoriasis. A disintegrin and metalloproteinase with thrombospondin motifs (ADAMTS) is a large family of proteoglycanase enzymes that show proteolytic activity. The expression levels of ADAMTS proteases in osteoarthritis and rheumatoid arthritis are upregulated. However, their expression levels in PsA patients have not been examined yet. The aim of this study was to determine the serum levels of ADAMTS4 and ADAMTS8 in PsA patients.