Central irisin administration suppresses thyroid hormone production but increases energy consumption in rats

Tekin S., Erden Y., Ozyalın F., Onalan E. E., Çiğremiş Y., Çolak C., ...Daha Fazla

NEUROSCIENCE LETTERS, cilt.674, ss.136-141, 2018 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 674
  • Basım Tarihi: 2018
  • Doi Numarası: 10.1016/j.neulet.2018.03.046
  • Dergi Adı: NEUROSCIENCE LETTERS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.136-141
  • Anahtar Kelimeler: Irisin, HPT axis, Thyroid hormones, Energy metabolism, Uncoupling proteins, CIRCULATING IRISIN, FOOD-INTAKE, UNCOUPLING PROTEINS, FEEDING-BEHAVIOR, ADIPOSE-TISSUE, OBESITY, MYOKINE, MUSCLE, EXPRESSION, EXERCISE
  • İnönü Üniversitesi Adresli: Evet

Özet

Irisin, which is secreted from the skeletal muscle in response to physical exercise and defined as a thermogenic peptide, may play an important role in energy metabolism. Thyroid hormones, which are one of the other influential factors on the metabolic status, increase heat production and are the main regulators of energy metabolism. This study was conducted to determine the possible effects of irisin administration on thyroid hormones.