Cytoprotective effects of amifostine, ascorbic acid and N-acetylcysteine against methotrexate-induced hepatotoxicity in rats


Akbulut S. , Elbe H., Eris C., Doğan Z., Toprak G., Otan E. , ...Daha Fazla

WORLD JOURNAL OF GASTROENTEROLOGY, cilt.20, ss.10158-10165, 2014 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 20
  • Basım Tarihi: 2014
  • Doi Numarası: 10.3748/wjg.v20.i29.10158
  • Dergi Adı: WORLD JOURNAL OF GASTROENTEROLOGY
  • Sayfa Sayıları: ss.10158-10165

Özet

AIM: To investigate the potential role of oxidative stress and the possible therapeutic effects of N-acetyl cysteine (NAC), amifostine (AMF) and ascorbic acid (ASC) in methotrexate (MTX)-induced hepatotoxicity.