Can T2 blackout effect be a marker of iron accumulation in brains of multiple sclerosis patients?

ERBAY M. F., KAMIŞLI Ö., Karatoprak N. B.

BRITISH JOURNAL OF RADIOLOGY, cilt.93, sa.1113, 2020 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 93 Sayı: 1113
  • Basım Tarihi: 2020
  • Doi Numarası: 10.1259/bjr.20200552
  • Dergi Adı: BRITISH JOURNAL OF RADIOLOGY
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, EMBASE, MEDLINE, Veterinary Science Database
  • İnönü Üniversitesi Adresli: Evet

Özet

Objective : T2 blackout (TBO) effect, which is a common finding in the brains of multiple sclerosis (MS) patients and older population that are imaged for other reasons on diffusion weighted imagings (DWI) and apparent diffusion coefficient (ADC) map show the existence of paramagnetic materials in the tissue. Because iron is known to accumulate in especially deep gray matter (DGM) structures in MS brains, we aimed to investigate the relationship between TBO and clinico-radiological parameters that may be iron-related in MS.