Synthesis and characterization of novel phosphoramidates containing benzimidazole moiety

Yilmaz U., KÜÇÜKBAY H.

PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS, cilt.191, sa.1, ss.140-143, 2016 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 191 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1080/10426507.2015.1067209
  • Dergi Adı: PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.140-143
  • Anahtar Kelimeler: Benzimidazole, diphenyl chlorophosphate, phosphoramidates, phosphonate, argon atmosphere, ester of phosphonic acid, ION-COORDINATING PROPERTIES, ISOMERIC EQUILIBRIA, ACID, PHOSPHONATE, INHIBITORS, PRODRUGS, DESIGN, QUANTIFICATION, DERIVATIVES, COPOLYMERS
  • İnönü Üniversitesi Adresli: Evet

Özet

Novel heterocyclic phosphoramidates were synthesized by a nucleophilic substitution reaction of 2-substitutedbenzimidazoles and diphenyl chlorophosphate (ClPO3Ph2) in the presence of potassium hydroxide (KOH) under an argon atmosphere. The structures of the phosphoramidates were characterized by NMR, IR, melting point, and elemental analysis.