Comparison of major lymphocyte subpopulations and recent thymic emigrants in patients with ataxia telangiectasia and age-matched healthy groups


Celiksoy M. H. , Topal E., Yildiran A.

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, cilt.43, ss.477-481, 2015 (SCI İndekslerine Giren Dergi) identifier identifier identifier

  • Cilt numarası: 43 Konu: 5
  • Basım Tarihi: 2015
  • Doi Numarası: 10.1016/j.aller.2014.06.007
  • Dergi Adı: ALLERGOLOGIA ET IMMUNOPATHOLOGIA
  • Sayfa Sayıları: ss.477-481

Özet

Background: Ataxia telangiectasia (A-T) is a genetic disorder caused by the homozygous mutation of the A-T mutated gene. It is frequently associated with variable degrees of cellular and humoral immunodeficiency. However, the immune defects in A-T patients are not well characterized. To the best of our knowledge, no studies have focused on the major lymphocyte subpopulations and recent thymic emigrants of A-T patients in comparison with age-matched healthy controls.