Comparison of major lymphocyte subpopulations and recent thymic emigrants in patients with ataxia telangiectasia and age-matched healthy groups


Celiksoy M. H. , Topal E., Yildiran A.

ALLERGOLOGIA ET IMMUNOPATHOLOGIA, vol.43, no.5, pp.477-481, 2015 (Journal Indexed in SCI) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 43 Issue: 5
  • Publication Date: 2015
  • Doi Number: 10.1016/j.aller.2014.06.007
  • Title of Journal : ALLERGOLOGIA ET IMMUNOPATHOLOGIA
  • Page Numbers: pp.477-481

Abstract

Background: Ataxia telangiectasia (A-T) is a genetic disorder caused by the homozygous mutation of the A-T mutated gene. It is frequently associated with variable degrees of cellular and humoral immunodeficiency. However, the immune defects in A-T patients are not well characterized. To the best of our knowledge, no studies have focused on the major lymphocyte subpopulations and recent thymic emigrants of A-T patients in comparison with age-matched healthy controls.