Enzyme-based Amperometric Biosensors Used in CGM Technology


Academic Conference on Robotization, Engineering and Artificial Intelligence (AC-REAI 2019), Prag, Czech Republic, 8 - 10 August 2019, pp.186-193

  • Publication Type: Conference Paper / Full Text
  • City: Prag
  • Country: Czech Republic
  • Page Numbers: pp.186-193


Nanotechnology has considerable potential for improving the care of individuals with diabetes. Glucose nanosensors are being incorporated in implantable devices that enable more accurate and real-time tracking of blood glucose status, and additionally, provide the basis for glucose sensitive nanoparticles that better imitation the body’s physiological needs for insulin. The enzyme-based glucose sensor is a biosensor connected to a transducer to produce a digital signal. The most important advantage of the biosensors is to simplify the analysis and enable analytical monitoring. The amperometric biosensor is one of the enzyme-based biosensors that converts biological recognition occurrences caused by electroactive species on the sensing surface to a current signal. This biosensor is an electrochemical sensor which is used in CGM (Continuous Glucose Monitoring) systems to provide continuous glucose monitoring. In this review, the structure of amperometric biosensors was explained, and the comparison of accuracy for these sensors belonging different companies was shown.